What You Need to Know About GLP-1 Medicines for Weight Loss and Diabetes
In recent years, GLP-1 receptor agonists (GLP-1 RAs) have gained significant attention for their dual role in managing Type 2 diabetes and supporting weight loss. Medications like Ozempic, Wegovy, Rybelsus, and Mounjaro are becoming more widely discussed — but it's essential to separate facts from hype.
This blog highlights key guidance from the UK government and MHRA, ensuring you have trustworthy, up-to-date information before considering these treatments.
What Are GLP-1 Medicines?
GLP-1 receptor agonists are a class of prescription medicines that mimic the action of the GLP-1 hormone naturally found in the gut. This hormone helps regulate blood sugar levels and promotes feelings of fullness, which can lead to reduced appetite and weight loss.
These medicines are used primarily for two purposes:
- Managing Type 2 diabetes
- Supporting weight loss in individuals with obesity
Which Medications Are Commonly Used?
Here are some of the most recognized GLP-1 medicines in the UK:
| Medicine | Brand Names | Licensed Use |
|---|---|---|
| Semaglutide | Wegovy, Ozempic, Rybelsus | Diabetes (Ozempic, Rybelsus); Weight loss (Wegovy) |
| Tirzepatide | Mounjaro | Type 2 diabetes; Weight loss (licensed separately) |
| Liraglutide | Saxenda, Victoza | Diabetes (Victoza); Weight loss (Saxenda) |
Important Safety Warnings
- Do not use GLP-1 medicines for cosmetic weight loss. These are powerful drugs meant for specific medical conditions, not casual slimming.
- Avoid unregulated sources like online vendors or beauty clinics. Counterfeit products—especially powders or mixed pens—can be dangerous or even life-threatening.
- Women on oral contraceptives should be aware: Tirzepatide (Mounjaro) may reduce contraceptive effectiveness. Additional contraception is advised for four weeks after starting or adjusting the dose.
- Side effects can include nausea, vomiting, diarrhoea, gallbladder problems, and rare risks like pancreatitis or pulmonary aspiration during surgery.
- Always report any adverse reactions through the MHRA Yellow Card Scheme.
What to Do Next
If you're considering a GLP-1 medicine for weight loss or diabetes, start by speaking with a registered UK prescriber. They will assess your medical history, current health goals, and eligibility.
You can also take a confidential health check to determine if you qualify for a clinically guided weight management service that aligns with NHS-informed care.
In Summary
GLP-1 medicines like Wegovy, Ozempic, and Mounjaro offer promising results when used responsibly. But they are not a quick fix and should never be sourced outside regulated medical channels.
Make your health a priority. Trust qualified healthcare providers, understand the risks and benefits, and ensure you're taking safe, evidence-based steps toward your wellness goals.